Synaptic Transmission and Modulation in Parasympathetic Ganglia.

Endogenous neurokinins facilitate synaptic transmission in guinea pig airway parasympathetic ganglia.

Neurokinin-containing nerve fibers were localized to guinea pig airway parasympathetic ganglia in control tissues but not in tissues pretreated with capsaicin. The purpose of the present study was to determine whether neurokinins, released during axonal reflexes or after antidromic afferent nerve stimulation, modulate ganglionic synaptic neurotransmission. The neurokinin type 3 (NK(3)) receptor...

Modulation of Synaptic Amplification in Sympathetic Ganglia

Slow synaptic transmission in frog sympathetic ganglia.

Bullfrog ganglia contain two classes of neurone, B and C cells, which receive different inputs and exhibit different slow synaptic potentials. B cells, to which most effort has been directed, possess slow and late slow EPSPs. The sEPSP reflects a muscarinic action of acetylcholine released from boutons on B cells, whereas the late sEPSP is caused by a peptide (similar to teleost LHRH) released ...

-Amyloid Modulation of Synaptic Transmission and Plasticity

Deepa V. Venkitaramani,1 Jeannie Chin,2 William J. Netzer,3 Gunnar K. Gouras,4 Sylvain Lesne,5 Roberto Malinow,6 and Paul J. Lombroso1 1Child Study Center, Yale University School of Medicine, New Haven, Connecticut 06520, 2Gladstone Institute of Neurological Disease, University of California, San Francisco, San Francisco, California 94158, 3Laboratory of Molecular and Cellular Neuroscience, and...

Synaptic Transmission at Single Boutons in Sympathetic Ganglia.

Synaptic transmission has traditionally been studied at the level of the entire nerve terminal rather than at one of its constituent boutons. Autonomic ganglia provide preparations for recording from individual boutons, as well as for determining the calcium transients necessary for transmitter release at these boutons. The results suggest a new paradigm for synaptic transmission.